Mecanismos Moleculares Reguladores da Embriogênese do Tubo Digestivo

Reis, Alice H. ; Amado, Nathalia G. ; Abreu, José G.

Resumo:

O endoderma origina uma vasta rede de tipos celulares epiteliais altamente especializados que compõem os sistemas respiratório e digestório, e contribui para a formação de órgãos associados, tais como: tireóide, timo, pulmões, fígado, sistema biliar e pâncreas. Perturbações nas funções dos órgãos de origem endodermal são a causa de numerosas doenças humanas. Pesquisas básicas, que visam entender a formação dos órgãos endodermais, tem fornecido o entendimento da base genética de muitas doenças congênitas humanas, e a pesquisa continuada, provavelmente tornará possível o crescimento de tecidos de órgãos endodermais in vitro para futuras terapias baseadas em transplantes (Spence e Wells, 2007; Zorn e Wells, 2009).

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DOI: 10.5151/9788580391893-08

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Como citar:

REIS, Alice H.; AMADO, Nathalia G.; ABREU, José G.; "Mecanismos Moleculares Reguladores da Embriogênese do Tubo Digestivo", p. 197-214. Sistema digestório: integração básico-clínica. São Paulo: Blucher, 2016.
ISBN: 9788580391893, DOI 10.5151/9788580391893-08