Fisiologia Pacreática: Pâncreas Endócrino

Montenegro Jr., Renan, Chaves, Mariana, Fernandes, Virginia

doi:10.5151/9788580391893-20

Fisiologia Pacreática: Pâncreas Endócrino

Montenegro Jr., Renan ; Chaves, Mariana ; Fernandes, Virginia

Resumo:

O pâncreas é uma glândula retroperitoneal, lobulada, com peso entre 60 e 170g, medindo de 12 a 25cm. É dividido em três partes: cabeça (proximal), corpo e cauda (distal). A primeira encontra-se em íntimo contato com o duodeno, enquanto a última com o hilo esplênico efl exura cólica esquerda. O canal de Winsurg é um ducto excretório, o qual acompanha toda a extensão do pâncreas. Conecta-se ao duodeno através da ampola de Vater, onde se junta ao ducto biliar. O esfíncter de Oddi, juntamente com a ampola de Vater, regula a secreção pancreática no trato gastrointestinal.

Mais de 95% da massa pancreática corresponde a células exócrinas, agrupadas em lóbulos (ácinos). O ácinos estão conectados aos ductos pancreáticos, formando uma espécie de rede. As células acinares são responsáveis pela liberação de enzimas digestivas e outros componentes não enzimáticos (bicarbonato) no duodeno, para facilitar a digestão.As Ilhotas de Langerhans são responsáveis pela função endócrina do pâncreas. São agrupados de células, envolvidas por tecido exócrino, altamente vascularizados e inervados, compostos por vários tipos diferentes de células, sendo as principais: α, β, δ e células PP.

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DOI: 10.5151/9788580391893-20

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Como citar:

MONTENEGRO JR., Renan; CHAVES, Mariana; FERNANDES, Virginia; "Fisiologia Pacreática: Pâncreas Endócrino", p. 523-574. Sistema digestório: integração básico-clínica. São Paulo: Blucher, 2016.
ISBN: 9788580391893, DOI 10.5151/9788580391893-20